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The SGLT-2 inhibitor empagliflozin improves myocardial strain, reduces cardiac fibrosis and pro-inflammatory cytokines in non-diabetic mice treated with doxorubicin.
Quagliariello, Vincenzo; De Laurentiis, Michelino; Rea, Domenica; Barbieri, Antonio; Monti, Maria Gaia; Carbone, Andreina; Paccone, Andrea; Altucci, Lucia; Conte, Mariarosaria; Canale, Maria Laura; Botti, Gerardo; Maurea, Nicola.
Affiliation
  • Quagliariello V; Division of Cardiology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy. quagliariello.enzo@gmail.com.
  • De Laurentiis M; Breast Unit, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.
  • Rea D; SSD Sperimentazione Animale, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.
  • Barbieri A; SSD Sperimentazione Animale, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.
  • Monti MG; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Carbone A; Division of Cardiology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.
  • Paccone A; Division of Cardiology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.
  • Altucci L; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Via L. De Crecchio 7, 80138, Naples, Italy.
  • Conte M; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Via L. De Crecchio 7, 80138, Naples, Italy.
  • Canale ML; Cardiology Division, Azienda USL Toscana Nord-Ovest, Versilia Hospital, Lido Di Camaiore, Italy.
  • Botti G; Scientific Direction, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.
  • Maurea N; Division of Cardiology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy. n.maurea@istitutotumori.na.it.
Cardiovasc Diabetol ; 20(1): 150, 2021 07 23.
Article in En | MEDLINE | ID: mdl-34301253
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Benzhydryl Compounds / Cytokines / Ventricular Function, Left / Inflammation Mediators / Myocytes, Cardiac / Sodium-Glucose Transporter 2 Inhibitors / Glucosides / Heart Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cardiovasc Diabetol Year: 2021 Document type: Article
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Benzhydryl Compounds / Cytokines / Ventricular Function, Left / Inflammation Mediators / Myocytes, Cardiac / Sodium-Glucose Transporter 2 Inhibitors / Glucosides / Heart Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cardiovasc Diabetol Year: 2021 Document type: Article