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Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine.
Oberhardt, Valerie; Luxenburger, Hendrik; Kemming, Janine; Schulien, Isabel; Ciminski, Kevin; Giese, Sebastian; Csernalabics, Benedikt; Lang-Meli, Julia; Janowska, Iga; Staniek, Julian; Wild, Katharina; Basho, Kristi; Marinescu, Mircea Stefan; Fuchs, Jonas; Topfstedt, Fernando; Janda, Ales; Sogukpinar, Oezlem; Hilger, Hanna; Stete, Katarina; Emmerich, Florian; Bengsch, Bertram; Waller, Cornelius F; Rieg, Siegbert; Boettler, Tobias; Zoldan, Katharina; Kochs, Georg; Schwemmle, Martin; Rizzi, Marta; Thimme, Robert; Neumann-Haefelin, Christoph; Hofmann, Maike.
Affiliation
  • Oberhardt V; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Luxenburger H; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Kemming J; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Schulien I; IMM-PACT, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Ciminski K; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Giese S; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Csernalabics B; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Lang-Meli J; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Janowska I; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Staniek J; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Wild K; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Basho K; IMM-PACT, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Marinescu MS; Department of Rheumatology and Clinical Immunology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Fuchs J; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Topfstedt F; Department of Rheumatology and Clinical Immunology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Janda A; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Sogukpinar O; Faculty of Chemistry and Pharmacy, University of Freiburg, Freiburg, Germany.
  • Hilger H; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Stete K; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Emmerich F; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Bengsch B; Department of Rheumatology and Clinical Immunology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Waller CF; Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.
  • Rieg S; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Sagar; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Boettler T; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Zoldan K; Institute for Transfusion Medicine and Gene Therapy, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Kochs G; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Schwemmle M; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.
  • Rizzi M; Department of Haematology, Oncology & Stem Cell Transplantation, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Thimme R; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Neumann-Haefelin C; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Hofmann M; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Nature ; 597(7875): 268-273, 2021 09.
Article in En | MEDLINE | ID: mdl-34320609
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 4_TD Database: MEDLINE Main subject: Vaccines, Synthetic / Vaccination / CD8-Positive T-Lymphocytes / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: Nature Year: 2021 Document type: Article
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 4_TD Database: MEDLINE Main subject: Vaccines, Synthetic / Vaccination / CD8-Positive T-Lymphocytes / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: Nature Year: 2021 Document type: Article