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Engineering sperm-binding IgG antibodies for the development of an effective nonhormonal female contraception.
Shrestha, Bhawana; Schaefer, Alison; Zhu, Yong; Saada, Jamal; Jacobs, Timothy M; Chavez, Elizabeth C; Olmsted, Stuart S; Cruz-Teran, Carlos A; Vaca, Gabriela Baldeon; Vincent, Kathleen; Moench, Thomas R; Lai, Samuel K.
Affiliation
  • Shrestha B; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Schaefer A; UNC/NCSU Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Zhu Y; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • Saada J; Department of Ophthalmology, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • Jacobs TM; Division of Pharmacoengineering and Molecular Pharmaceutics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Chavez EC; Dualogics LLC, Durham, NC 27713, USA.
  • Olmsted SS; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Cruz-Teran CA; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Vaca GB; Division of Pharmacoengineering and Molecular Pharmaceutics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Vincent K; Divisions of Infectious Disease and Obstetrics & Gynecology, Boston University School of Medicine, Boston, MA 02118, USA.
  • Moench TR; Division of Gynecology, Department of Obstetrics and Gynecology, Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • Lai SK; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA.
Sci Transl Med ; 13(606)2021 08 11.
Article in En | MEDLINE | ID: mdl-34380769

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sperm Motility / Immunoglobulin G Limits: Animals / Female / Humans / Male / Pregnancy Language: En Journal: Sci Transl Med Year: 2021 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sperm Motility / Immunoglobulin G Limits: Animals / Female / Humans / Male / Pregnancy Language: En Journal: Sci Transl Med Year: 2021 Document type: Article