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Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses.
Rajasekaran, Swetha; Siddiqui, Jalal; Rakijas, Jessica; Nicolay, Brandon; Lin, Chenyu; Khan, Eshan; Patel, Rahi; Morris, Robert; Wyler, Emanuel; Boukhali, Myriam; Balasubramanyam, Jayashree; Ranjith Kumar, R; Van Rechem, Capucine; Vogel, Christine; Elchuri, Sailaja V; Landthaler, Markus; Obermayer, Benedikt; Haas, Wilhelm; Dyson, Nicholas; Miles, Wayne.
Affiliation
  • Rajasekaran S; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
  • Siddiqui J; The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
  • Rakijas J; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
  • Nicolay B; The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
  • Lin C; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
  • Khan E; The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
  • Patel R; Massachusetts General Hospital Cancer Center, Charlestown, MA, USA.
  • Morris R; Harvard Medical School, Boston, MA, USA.
  • Wyler E; Agios Pharmaceutical, Cambridge, MA, USA.
  • Boukhali M; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
  • Balasubramanyam J; The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
  • Ranjith Kumar R; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
  • Van Rechem C; The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
  • Vogel C; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
  • Elchuri SV; The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
  • Landthaler M; Massachusetts General Hospital Cancer Center, Charlestown, MA, USA.
  • Obermayer B; Harvard Medical School, Boston, MA, USA.
  • Haas W; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Dyson N; Massachusetts General Hospital Cancer Center, Charlestown, MA, USA.
  • Miles W; Harvard Medical School, Boston, MA, USA.
Commun Biol ; 4(1): 977, 2021 08 17.
Article in En | MEDLINE | ID: mdl-34404904
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinoblastoma / Retinal Neoplasms / Ubiquitin-Protein Ligases / Retinoblastoma Binding Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Commun Biol Year: 2021 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinoblastoma / Retinal Neoplasms / Ubiquitin-Protein Ligases / Retinoblastoma Binding Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Commun Biol Year: 2021 Document type: Article