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BC-N102 suppress breast cancer tumorigenesis by interfering with cell cycle regulatory proteins and hormonal signaling, and induction of time-course arrest of cell cycle at G1/G0 phase.
Lawal, Bashir; Kuo, Yu-Cheng; Wu, Alexander T H; Huang, Hsu-Shan.
Affiliation
  • Lawal B; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan.
  • Kuo YC; Graduate Institute for Cancer Biology & Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.
  • Wu ATH; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei11031, Taiwan.
  • Huang HS; School of Post-baccalaureate Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung40402, Taiwan.
Int J Biol Sci ; 17(12): 3224-3238, 2021.
Article in En | MEDLINE | ID: mdl-34421361
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Receptors, Estrogen / Resting Phase, Cell Cycle / G1 Phase / Cell Cycle Proteins / Cell Cycle Checkpoints / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Int J Biol Sci Year: 2021 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Receptors, Estrogen / Resting Phase, Cell Cycle / G1 Phase / Cell Cycle Proteins / Cell Cycle Checkpoints / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Int J Biol Sci Year: 2021 Document type: Article