Nanopore sequencing and de novo assembly of a misidentified Camelpox vaccine reveals putative epigenetic modifications and alternate protein signal peptides.

Saud, Zack; Hitchings, Matthew D; Butt, Tariq M

Saud, Zack; Hitchings, Matthew D; Butt, Tariq M.

Affiliation

Saud Z; Department of Biosciences, College of Science, Swansea University, Singleton Park, Swansea, SA2 8PP, Wales, UK. zack.saud@swansea.ac.uk.
Hitchings MD; Swansea University Medical School, Swansea University, Singleton Park, Swansea, Sa2 8PP, Wales, UK.
Butt TM; Department of Biosciences, College of Science, Swansea University, Singleton Park, Swansea, SA2 8PP, Wales, UK.

Sci Rep ; 11(1): 17758, 2021 09 07.

Article in En | MEDLINE | ID: mdl-34493784

Subject(s)

Defective Viruses/genetics; Epigenome; Genome, Viral; Nanopore Sequencing; Orthopoxvirus/genetics; Protein Sorting Signals/genetics; Sequence Analysis, DNA/methods; Vaccinia virus/genetics; Viral Proteins/genetics; Viral Vaccines; Amino Acid Motifs; Amino Acid Sequence; DNA Viruses/genetics; Molecular Sequence Annotation; Orthopoxvirus/immunology; Sequence Deletion; Software; Species Specificity; United Arab Emirates; Vaccines, Attenuated

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Full text: 1 Collection: 01-internacional Health context: 4_TD Database: MEDLINE Main subject: Vaccinia virus / Viral Proteins / Protein Sorting Signals / Viral Vaccines / Genome, Viral / Sequence Analysis, DNA / Orthopoxvirus / Defective Viruses / Epigenome / Nanopore Sequencing Country/Region as subject: Asia Language: En Journal: Sci Rep Year: 2021 Document type: Article

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