The Prognosis of Baseline Mitral Regurgitation in Patients with Transcatheter Aortic Valve Implantation.
J Clin Med
; 10(17)2021 Sep 02.
Article
in En
| MEDLINE
| ID: mdl-34501424
ABSTRACT
Mitral regurgitation (MR) is the most common valvular lesion in transcatheter aortic valve implantation (TAVI) recipients. This study aims to assess the long-term prognostic impact of baseline MR in TAVI patients. METHODS:
Adult patients who underwent TAVI were identified in the French National Hospital Discharge Database. All-cause and cardiovascular mortality, stroke, and rehospitalization with heart failure (HF) were compared in TAVI patients with and without baseline MR and tricuspid regurgitation (TR), respectively; the associations of MR and TR with the outcomes were assessed by Cox regression.RESULTS:
Baseline MR was identified in 8240 TAVI patients. Patients with baseline MR have higher yearly incidence of all-cause mortality (HR 1.192, 95% confidence interval CI 1.125-1.263), cardiovascular mortality (HR 1.313, 95%CI 1.210-1.425), and rehospitalization for heart failure (HF) (HR 1.411, 95%CI 1.340-1.486) compared to those without, except for stroke rate (HR 0.988, 95%CI 0.868-1.124). Neither baseline MR nor TR was an independent risk predictor for all-cause mortality or cardiovascular mortality in TAVI patients. Baseline MR was independently associated with rehospitalization for HF in TAVI patients.CONCLUSIONS:
Baseline MR and TR were associated with increased all-cause and cardiovascular mortality post-TAVI, however, neither of them was independent predictor for all-cause or cardiovascular mortality.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Prognostic_studies
Language:
En
Journal:
J Clin Med
Year:
2021
Document type:
Article