l-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity.

Khedr, Naglaa F; Werida, Rehab H

Khedr, Naglaa F; Werida, Rehab H.

Affiliation

Khedr NF; Faculty of Pharmacy, Department of Biochemistry, Tanta University, Tanta, Egypt. Electronic address: naglaa.khedr@pharm.tanta.edu.eg.
Werida RH; Faculty of Pharmacy, Clinical Pharmacy & Pharmacy Practice Department, Damanhur University, El- Bahiara, Egypt. Electronic address: rehabwrieda@pharm.dmu.edu.eg.

Life Sci ; 290: 120025, 2022 Feb 01.

Article in En | MEDLINE | ID: mdl-34637798

Subject(s)

Carnitine/pharmacology; Testis/drug effects; Trazodone/adverse effects; Animals; Antioxidants/pharmacology; Autophagy/drug effects; Autophagy/physiology; Carnitine/metabolism; Inflammation/physiopathology; Lipid Peroxidation; Male; Oxidative Stress/drug effects; Oxidative Stress/physiology; Rats; Rats, Wistar; Sperm Count/methods; Spermatogenesis/drug effects; Spermatozoa/drug effects; Testis/metabolism; Trazodone/pharmacology; Trazodone/toxicity

Key words

Autophagy; Oxidative stress; Testes; Trazadone; l-carnitine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Testis / Trazodone / Carnitine Limits: Animals Language: En Journal: Life Sci Year: 2022 Document type: Article

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