Your browser doesn't support javascript.
loading
IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies.
Friedrich, Matthias; Pohin, Mathilde; Jackson, Matthew A; Korsunsky, Ilya; Bullers, Samuel J; Rue-Albrecht, Kevin; Christoforidou, Zoe; Sathananthan, Dharshan; Thomas, Tom; Ravindran, Rahul; Tandon, Ruchi; Peres, Raphael Sanches; Sharpe, Hannah; Wei, Kevin; Watts, Gerald F M; Mann, Elizabeth H; Geremia, Alessandra; Attar, Moustafa; McCuaig, Sarah; Thomas, Lloyd; Collantes, Elena; Uhlig, Holm H; Sansom, Stephen N; Easton, Alistair; Raychaudhuri, Soumya; Travis, Simon P; Powrie, Fiona M.
Affiliation
  • Friedrich M; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Pohin M; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Jackson MA; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Korsunsky I; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
  • Bullers SJ; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Rue-Albrecht K; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Christoforidou Z; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Sathananthan D; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Thomas T; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Ravindran R; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Tandon R; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
  • Peres RS; Translational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • Sharpe H; Translational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • Wei K; Translational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • Watts GFM; Translational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • Mann EH; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Geremia A; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Attar M; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • McCuaig S; Translational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • Thomas L; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Collantes E; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Easton A; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Raychaudhuri S; Translational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • Travis SP; Translational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • Powrie FM; Translational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
Nat Med ; 27(11): 1970-1981, 2021 11.
Article in En | MEDLINE | ID: mdl-34675383
Subject(s)
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inflammatory Bowel Diseases / Interleukin-1 / Stromal Cells / Neutrophil Infiltration / Neutrophils Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Nat Med Year: 2021 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inflammatory Bowel Diseases / Interleukin-1 / Stromal Cells / Neutrophil Infiltration / Neutrophils Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Nat Med Year: 2021 Document type: Article