Single nucleotide polymorphisms and copy-number variations in the Trypanosoma brucei repeat (TBR) sequence can be used to enhance amplification and genotyping of Trypanozoon strains.

Van Reet, Nick; Patient Pyana, Pati; Dehou, Sara; Bebronne, Nicolas; Deborggraeve, Stijn; Büscher, Philippe

Van Reet, Nick; Patient Pyana, Pati; Dehou, Sara; Bebronne, Nicolas; Deborggraeve, Stijn; Büscher, Philippe.

Affiliation

Van Reet N; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.
Patient Pyana P; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Dehou S; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.
Bebronne N; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.
Deborggraeve S; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.

PLoS One ; 16(10): e0258711, 2021.

Article in En | MEDLINE | ID: mdl-34695154

Subject(s)

DNA Copy Number Variations; DNA, Protozoan/genetics; Polymorphism, Single Nucleotide; Protozoan Proteins/genetics; Repetitive Sequences, Nucleic Acid; Trypanosoma brucei brucei/genetics; Trypanosomiasis, African/genetics; DNA, Protozoan/analysis; Trypanosoma brucei brucei/growth & development; Trypanosomiasis, African/parasitology

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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Trypanosoma brucei brucei / Trypanosomiasis, African / Repetitive Sequences, Nucleic Acid / Protozoan Proteins / DNA, Protozoan / Polymorphism, Single Nucleotide / DNA Copy Number Variations Type of study: Risk_factors_studies Language: En Journal: PLoS One Year: 2021 Document type: Article

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