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Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway.
Abegg, Daniel; Tomanik, Martin; Qiu, Nan; Pechalrieu, Dany; Shuster, Anton; Commare, Bruno; Togni, Antonio; Herzon, Seth B; Adibekian, Alexander.
Affiliation
  • Abegg D; Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States.
  • Tomanik M; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
  • Qiu N; Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States.
  • Pechalrieu D; Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States.
  • Shuster A; Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States.
  • Commare B; Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 2, CH-8093 Zürich, Switzerland.
  • Togni A; Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 2, CH-8093 Zürich, Switzerland.
  • Herzon SB; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
  • Adibekian A; Department of Pharmacology, Yale School of Medicine, New Haven, Connecticut 06520, United States.
J Am Chem Soc ; 143(48): 20332-20342, 2021 12 08.
Article in En | MEDLINE | ID: mdl-34817176
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Molecular Probes / Cysteine / Proteomics / Heterocyclic Compounds, 2-Ring / Hydrocarbons, Fluorinated Limits: Humans Language: En Journal: J Am Chem Soc Year: 2021 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Molecular Probes / Cysteine / Proteomics / Heterocyclic Compounds, 2-Ring / Hydrocarbons, Fluorinated Limits: Humans Language: En Journal: J Am Chem Soc Year: 2021 Document type: Article