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The von Willebrand factor A-1 domain binding aptamer BT200 elevates plasma levels of von Willebrand factor and factor VIII: a first-in-human trial.
Kovacevic, Katarina D; Grafeneder, Jürgen; Schörgenhofer, Christian; Gelbenegger, Georg; Gager, Gloria; Firbas, Christa; Quehenberger, Peter; Jilma-Stohlawetz, Petra; Bileck, Andrea; Zhu, Shuhao; Gilbert, James C; Beliveau, Martin; Jilma, Bernd; Derhaschnig, Ulla.
Affiliation
  • Kovacevic KD; Department of Clinical Pharmacology. katarina.kovacevic@meduniwien.ac.at.
  • Grafeneder J; Department of Clinical Pharmacology.
  • Schörgenhofer C; Department of Clinical Pharmacology.
  • Gelbenegger G; Department of Clinical Pharmacology.
  • Gager G; Department of Clinical Pharmacology.
  • Firbas C; Department of Clinical Pharmacology.
  • Quehenberger P; Clinical Institute of Laboratory Medicine, Medical University of Vienna.
  • Jilma-Stohlawetz P; Clinical Institute of Laboratory Medicine, Medical University of Vienna.
  • Bileck A; Joint Metabolome Facility, University of Vienna and Medical University of Vienna, Vienna.
  • Zhu S; Guardian Therapeutics Inc., Lexington.
  • Gilbert JC; Guardian Therapeutics Inc., Lexington.
  • Beliveau M; Certara, Montreal.
  • Jilma B; Department of Clinical Pharmacology.
  • Derhaschnig U; Department of Clinical Pharmacology.
Haematologica ; 107(9): 2121-2132, 2022 09 01.
Article in En | MEDLINE | ID: mdl-34818873
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Von Willebrand Diseases / Von Willebrand Factor Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: Haematologica Year: 2022 Document type: Article
Fulltext
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Von Willebrand Diseases / Von Willebrand Factor Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: Haematologica Year: 2022 Document type: Article