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Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain.
Nabel, Katherine G; Clark, Sarah A; Shankar, Sundaresh; Pan, Junhua; Clark, Lars E; Yang, Pan; Coscia, Adrian; McKay, Lindsay G A; Varnum, Haley H; Brusic, Vesna; Tolan, Nicole V; Zhou, Guohai; Desjardins, Michaël; Turbett, Sarah E; Kanjilal, Sanjat; Sherman, Amy C; Dighe, Anand; LaRocque, Regina C; Ryan, Edward T; Tylek, Casey; Cohen-Solal, Joel F; Darcy, Anhdao T; Tavella, Davide; Clabbers, Anca; Fan, Yao; Griffiths, Anthony; Correia, Ivan R; Seagal, Jane; Baden, Lindsey R; Charles, Richelle C; Abraham, Jonathan.
Affiliation
  • Nabel KG; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Clark SA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Shankar S; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Pan J; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Clark LE; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Yang P; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Coscia A; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • McKay LGA; Department of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, MA 02118, USA.
  • Varnum HH; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Brusic V; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Tolan NV; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Zhou G; Center for Clinical Investigation, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Desjardins M; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Turbett SE; Division of Infectious Diseases, Department of Medicine, Centre Hospitalier de l'Université de Montréal, Montreal QC H2X 0C1, Canada.
  • Kanjilal S; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Sherman AC; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Dighe A; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • LaRocque RC; Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA 02215, USA.
  • Ryan ET; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Tylek C; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Cohen-Solal JF; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Darcy AT; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Tavella D; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02215, USA.
  • Clabbers A; AbbVie Bioresearch Center, Worcester, MA 01605, USA.
  • Fan Y; AbbVie Bioresearch Center, Worcester, MA 01605, USA.
  • Griffiths A; AbbVie Bioresearch Center, Worcester, MA 01605, USA.
  • Correia IR; AbbVie Bioresearch Center, Worcester, MA 01605, USA.
  • Seagal J; AbbVie Bioresearch Center, Worcester, MA 01605, USA.
  • Baden LR; AbbVie Bioresearch Center, Worcester, MA 01605, USA.
  • Charles RC; Department of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, MA 02118, USA.
  • Abraham J; AbbVie Bioresearch Center, Worcester, MA 01605, USA.
Science ; 375(6578): eabl6251, 2022 01 21.
Article in En | MEDLINE | ID: mdl-34855508
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 Database: MEDLINE Main subject: Antibodies, Neutralizing / Immune Evasion / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / Antibodies, Viral Type of study: Prognostic_studies Limits: Humans Language: En Journal: Science Year: 2022 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 Database: MEDLINE Main subject: Antibodies, Neutralizing / Immune Evasion / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / Antibodies, Viral Type of study: Prognostic_studies Limits: Humans Language: En Journal: Science Year: 2022 Document type: Article