Design and Synthesis of Indenoisoquinolines Targeting Topoisomerase I and Other Biological Macromolecules for Cancer Chemotherapy. | J Med Chem;64(24): 17572-17600, 2021 12 23. | MEDLINE

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Design and Synthesis of Indenoisoquinolines Targeting Topoisomerase I and Other Biological Macromolecules for Cancer Chemotherapy.

Cushman, Mark.

Affiliation

Cushman M; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.

J Med Chem ; 64(24): 17572-17600, 2021 12 23.

Article in En | MEDLINE | ID: mdl-34879200

Subject(s)

Antineoplastic Agents/pharmacology; DNA Topoisomerases, Type I/drug effects; Drug Design; Isoquinolines/chemistry; Isoquinolines/pharmacology; Drug Screening Assays, Antitumor; Humans; Isoquinolines/chemical synthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / DNA Topoisomerases, Type I / Isoquinolines / Antineoplastic Agents Limits: Humans Language: En Journal: J Med Chem Year: 2021 Document type: Article

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / DNA Topoisomerases, Type I / Isoquinolines / Antineoplastic Agents Limits: Humans Language: En Journal: J Med Chem Year: 2021 Document type: Article