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Neuropeptide Y1 receptor antagonism protects ß-cells and improves glycemic control in type 2 diabetes.
Yang, Chieh-Hsin; Ann-Onda, Danise; Lin, Xuzhu; Fynch, Stacey; Nadarajah, Shaktypreya; Pappas, Evan G; Liu, Xin; Scott, John W; Oakhill, Jonathan S; Galic, Sandra; Shi, Yanchuan; Moreno-Asso, Alba; Smith, Cassandra; Loudovaris, Thomas; Levinger, Itamar; Eizirik, Decio L; Laybutt, D Ross; Herzog, Herbert; Thomas, Helen E; Loh, Kim.
Affiliation
  • Yang CH; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia. Electronic address: jyang@svi.edu.au.
  • Ann-Onda D; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia.
  • Lin X; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia.
  • Fynch S; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia.
  • Nadarajah S; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia.
  • Pappas EG; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia.
  • Liu X; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia.
  • Scott JW; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, VIC, 3000, Australia; The Florey Institute of Neuroscience and Mental Health, Parkville, VIC, 3052, Australia.
  • Oakhill JS; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, VIC, 3000, Australia; Department of Medicine, University of Melbourne, Fitzroy, VIC, 3065, Australia.
  • Galic S; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia; Department of Medicine, University of Melbourne, Fitzroy, VIC, 3065, Australia.
  • Shi Y; Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, 2010, Australia; Faculty of Medicine, UNSW Australia, Sydney, 2052, Australia.
  • Moreno-Asso A; Institute of Health and Sport (IHES), Victoria University, Footscray, VIC, Australia; Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, VIC, Australia.
  • Smith C; Institute of Health and Sport (IHES), Victoria University, Footscray, VIC, Australia; Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, VIC, Australia.
  • Loudovaris T; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia; Department of Medicine, University of Melbourne, Fitzroy, VIC, 3065, Australia.
  • Levinger I; Institute of Health and Sport (IHES), Victoria University, Footscray, VIC, Australia; Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, VIC, Australia.
  • Eizirik DL; ULB Center for Diabetes Research, Medical Faculty, Universite Libre de Bruxelles (ULB), Brussels, Belgium; Indiana Biosciences Research Institute (IBRI), Indianapolis, IN, USA.
  • Laybutt DR; Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, 2010, Australia; Faculty of Medicine, UNSW Australia, Sydney, 2052, Australia.
  • Herzog H; Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, 2010, Australia; Faculty of Medicine, UNSW Australia, Sydney, 2052, Australia.
  • Thomas HE; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia; Department of Medicine, University of Melbourne, Fitzroy, VIC, 3065, Australia.
  • Loh K; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia; Department of Medicine, University of Melbourne, Fitzroy, VIC, 3065, Australia. Electronic address: kloh@svi.edu.au.
Mol Metab ; 55: 101413, 2022 01.
Article in En | MEDLINE | ID: mdl-34890851
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Receptors, Neuropeptide Y / Insulin-Secreting Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Metab Year: 2022 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Receptors, Neuropeptide Y / Insulin-Secreting Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Metab Year: 2022 Document type: Article