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Endothelial dysfunction contributes to severe COVID-19 in combination with dysregulated lymphocyte responses and cytokine networks.
Ruhl, Louisa; Pink, Isabell; Kühne, Jenny F; Beushausen, Kerstin; Keil, Jana; Christoph, Stella; Sauer, Andrea; Boblitz, Lennart; Schmidt, Julius; David, Sascha; Jäck, Hans-Martin; Roth, Edith; Cornberg, Markus; Schulz, Thomas F; Welte, Tobias; Höper, Marius M; Falk, Christine S.
Affiliation
  • Ruhl L; Institute of Transplant Immunology, MHH, D, Hanover, Germany.
  • Pink I; Department of Pneumology, MHH, D, Hanover, Germany.
  • Kühne JF; Institute of Transplant Immunology, MHH, D, Hanover, Germany.
  • Beushausen K; Institute of Transplant Immunology, MHH, D, Hanover, Germany.
  • Keil J; Institute of Transplant Immunology, MHH, D, Hanover, Germany.
  • Christoph S; Institute of Transplant Immunology, MHH, D, Hanover, Germany.
  • Sauer A; Department of Pneumology, MHH, D, Hanover, Germany.
  • Boblitz L; Department of Pneumology, MHH, D, Hanover, Germany.
  • Schmidt J; Department of Pneumology, MHH, D, Hanover, Germany.
  • David S; Department of Intensive Care Medicine, University of Zurich, CH, Zurich, Switzerland.
  • Jäck HM; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, D, Erlangen, Germany.
  • Roth E; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, D, Erlangen, Germany.
  • Cornberg M; Department of Gastroenterology Hepatology and Endocrinology, MHH, D, Hanover, Germany.
  • Schulz TF; Center for Individualized Infection Medicine CiiM, Hanover, Germany.
  • Welte T; Institute of Virology, MHH, D, Hanover, Germany.
  • Höper MM; German Center for Infection Research, DZIF, TTU-IICH, Marburg, Germany.
  • Falk CS; Excellence Cluster 2155 RESIST, MHH, Hanover, Germany.
Signal Transduct Target Ther ; 6(1): 418, 2021 12 10.
Article in En | MEDLINE | ID: mdl-34893580

Full text: 1 Collection: 01-internacional Health context: 4_TD / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Endothelium, Vascular / Blood Proteins / Cytokine Release Syndrome / SARS-CoV-2 / COVID-19 / Lymphopenia / Antibodies, Viral Type of study: Observational_studies Language: En Journal: Signal Transduct Target Ther Year: 2021 Document type: Article

Full text: 1 Collection: 01-internacional Health context: 4_TD / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Endothelium, Vascular / Blood Proteins / Cytokine Release Syndrome / SARS-CoV-2 / COVID-19 / Lymphopenia / Antibodies, Viral Type of study: Observational_studies Language: En Journal: Signal Transduct Target Ther Year: 2021 Document type: Article