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Oxidative stress induces Z-DNA-binding protein 1-dependent activation of microglia via mtDNA released from retinal pigment epithelial cells.
Saada, Jamal; McAuley, Ryan J; Marcatti, Michela; Tang, Tony Zifeng; Motamedi, Massoud; Szczesny, Bartosz.
Affiliation
  • Saada J; Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas, USA; Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas, USA.
  • McAuley RJ; Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch, Galveston, Texas, USA.
  • Marcatti M; Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas, USA; Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA.
  • Tang TZ; Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch, Galveston, Texas, USA.
  • Motamedi M; Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas, USA.
  • Szczesny B; Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas, USA; Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas, USA. Electronic address: baszczes@utmb.edu.
J Biol Chem ; 298(1): 101523, 2022 01.
Article in En | MEDLINE | ID: mdl-34953858

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / RNA-Binding Proteins / Microglia / Retinal Pigment Epithelium Limits: Humans Language: En Journal: J Biol Chem Year: 2022 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / RNA-Binding Proteins / Microglia / Retinal Pigment Epithelium Limits: Humans Language: En Journal: J Biol Chem Year: 2022 Document type: Article