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Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins.
De Marco Verissimo, Carolina; Jewhurst, Heather L; Dobó, József; Gál, Péter; Dalton, John P; Cwiklinski, Krystyna.
Affiliation
  • De Marco Verissimo C; Centre for One Health and Ryan Institute, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
  • Jewhurst HL; Centre for One Health and Ryan Institute, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
  • Dobó J; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
  • Gál P; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
  • Dalton JP; Centre for One Health and Ryan Institute, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
  • Cwiklinski K; Centre for One Health and Ryan Institute, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
PLoS Pathog ; 18(1): e1010226, 2022 01.
Article in En | MEDLINE | ID: mdl-35007288
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Complement System Proteins / Helminth Proteins / Mannose-Binding Lectin / Mannose-Binding Protein-Associated Serine Proteases / Fasciola hepatica Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2022 Document type: Article
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Complement System Proteins / Helminth Proteins / Mannose-Binding Lectin / Mannose-Binding Protein-Associated Serine Proteases / Fasciola hepatica Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2022 Document type: Article