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P. aeruginosa augments irradiation injury via 15-lipoxygenase-catalyzed generation of 15-HpETE-PE and induction of theft-ferroptosis.
Dar, Haider H; Epperly, Michael W; Tyurin, Vladimir A; Amoscato, Andrew A; Anthonymuthu, Tamil S; Souryavong, Austin B; Kapralov, Alexander A; Shurin, Galina V; Samovich, Svetlana N; St Croix, Claudette M; Watkins, Simon C; Wenzel, Sally E; Mallampalli, Rama K; Greenberger, Joel S; Bayir, Hülya; Kagan, Valerian E; Tyurina, Yulia Y.
Affiliation
  • Dar HH; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Epperly MW; Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
  • Tyurin VA; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Amoscato AA; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Anthonymuthu TS; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Souryavong AB; Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
  • Kapralov AA; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Shurin GV; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Samovich SN; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • St Croix CM; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Watkins SC; Department of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Wenzel SE; Department of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Mallampalli RK; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Greenberger JS; Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Bayir H; Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
  • Kagan VE; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Tyurina YY; Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
JCI Insight ; 7(4)2022 02 22.
Article in En | MEDLINE | ID: mdl-35041620
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas aeruginosa / Radiation Injuries, Experimental / Arachidonate 15-Lipoxygenase / Gene Expression Regulation, Neoplastic / Leukotrienes / Ferroptosis / Lipid Peroxides Limits: Animals / Female / Humans Language: En Journal: JCI Insight Year: 2022 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas aeruginosa / Radiation Injuries, Experimental / Arachidonate 15-Lipoxygenase / Gene Expression Regulation, Neoplastic / Leukotrienes / Ferroptosis / Lipid Peroxides Limits: Animals / Female / Humans Language: En Journal: JCI Insight Year: 2022 Document type: Article