Local graft versus host reaction in the xenogeneic system.
Arch Immunol Ther Exp (Warsz)
; 26(1-6): 1087-90, 1978.
Article
in En
| MEDLINE
| ID: mdl-35123
ABSTRACT
The injection of viable rat spleen cells beneath the renal capsule of cyclophosphamide (CY)-treated adult mice produced a localized graft versus host reaction (GvHR), manifested by the kidney enlargement index (KI). The optimal xenogeneic GvHR was obtained after injection of 30-50 million rat spleen cells into mouse recipients treated 24 hr before with CY, 200 mg/kg intraperitoneally (i.p.), and killed 7 days later. Splenomegaly in recipient mice suggested systemic dissemination of the local GvHR.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spleen
/
Transplantation, Heterologous
/
Graft vs Host Reaction
Limits:
Animals
Language:
En
Journal:
Arch Immunol Ther Exp (Warsz)
Year:
1978
Document type:
Article