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Targeting an alternate Wilms' tumor antigen 1 peptide bypasses immunoproteasome dependency.
Lahman, Miranda C; Schmitt, Thomas M; Paulson, Kelly G; Vigneron, Nathalie; Buenrostro, Denise; Wagener, Felecia D; Voillet, Valentin; Martin, Lauren; Gottardo, Raphael; Bielas, Jason; McElrath, Julie M; Stirewalt, Derek L; Pogosova-Agadjanyan, Era L; Yeung, Cecilia C; Pierce, Robert H; Egan, Daniel N; Bar, Merav; Hendrie, Paul C; Kinsella, Sinéad; Vakil, Aesha; Butler, Jonah; Chaffee, Mary; Linton, Jonathan; McAfee, Megan S; Hunter, Daniel S; Bleakley, Marie; Rongvaux, Anthony; Van den Eynde, Benoit J; Chapuis, Aude G; Greenberg, Philip D.
Affiliation
  • Lahman MC; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Schmitt TM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Paulson KG; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA 98115, USA.
  • Vigneron N; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Buenrostro D; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Wagener FD; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Voillet V; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Martin L; University of Washington School of Medicine, Seattle, WA 98115, USA.
  • Gottardo R; Ludwig Institute for Cancer Research, 1200 Brussels, Belgium.
  • Bielas J; de Duve Institute, Université Catholique de Louvain, Brussels, Belgium.
  • McElrath JM; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Stirewalt DL; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Pogosova-Agadjanyan EL; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Yeung CC; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Pierce RH; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Egan DN; Hutchinson Centre Research Institute of South Africa, Cape Town 8001, South Africa.
  • Bar M; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Hendrie PC; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Kinsella S; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Vakil A; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Butler J; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA 98115, USA.
  • Chaffee M; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Linton J; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • McAfee MS; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Hunter DS; University of Washington School of Medicine, Seattle, WA 98115, USA.
  • Bleakley M; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Rongvaux A; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Van den Eynde BJ; University of Washington School of Medicine, Seattle, WA 98115, USA.
  • Chapuis AG; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Greenberg PD; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Sci Transl Med ; 14(631): eabg8070, 2022 02 09.
Article in En | MEDLINE | ID: mdl-35138909

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / WT1 Proteins / Proteasome Endopeptidase Complex Limits: Animals / Humans Language: En Journal: Sci Transl Med Year: 2022 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / WT1 Proteins / Proteasome Endopeptidase Complex Limits: Animals / Humans Language: En Journal: Sci Transl Med Year: 2022 Document type: Article