Secondary Structures of the Transmembrane Domain of SARS-CoV-2 Spike Protein in Detergent Micelles.

Li, Qingxin; Huang, Qiwei; Kang, Congbao

Li, Qingxin; Huang, Qiwei; Kang, Congbao.

Affiliation

Li Q; Guangdong Provincial Engineering Laboratory of Biomass High Value Utilization, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China.
Huang Q; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), Singapore 138670, Singapore.
Kang C; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), Singapore 138670, Singapore.

Int J Mol Sci ; 23(3)2022 Jan 18.

Article in En | MEDLINE | ID: mdl-35162961

Subject(s)

Detergents/pharmacology; Spike Glycoprotein, Coronavirus/chemistry; Amino Acid Sequence; COVID-19/virology; Cell Membrane/metabolism; Cross-Linking Reagents/pharmacology; Detergents/chemistry; Humans; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Domains/drug effects; Protein Structure, Secondary/drug effects; SARS-CoV-2/chemistry; SARS-CoV-2/metabolism; Spike Glycoprotein, Coronavirus/drug effects; Spike Glycoprotein, Coronavirus/metabolism

Key words

COVID-19; NMR; S-protein; SARS-CoV-2; detergent micelles; transmembrane domain

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Detergents / Spike Glycoprotein, Coronavirus Limits: Humans Language: En Journal: Int J Mol Sci Year: 2022 Document type: Article

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