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Impact of Latent Tuberculosis on Diabetes.
Tepekule, Burcu; Kusejko, Katharina; Zeeb, Marius; Tarr, Philip E; Calmy, Alexandra; Battegay, Manuel; Furrer, Hansjakob; Cavassini, Matthias; Bernasconi, Enos; Notter, Julia; Günthard, Huldrych F; Nemeth, Johannes; Kouyos, Roger D.
Affiliation
  • Tepekule B; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Kusejko K; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
  • Zeeb M; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Tarr PE; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
  • Calmy A; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Battegay M; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
  • Furrer H; Department of Medicine and Division of Infectious Diseases and Hospital Epidemiology, Kantonsspital Baselland, University of Basel, Bruderholz, Switzerland.
  • Cavassini M; Division of Infectious Diseases, University Hospital Geneva, University of Geneva, Geneva, Switzerland.
  • Bernasconi E; Division of Infectious Diseases and Hospital Hygiene, University Hospital Basel, University of Basel, Basel, Switzerland.
  • Notter J; Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Günthard HF; Division of Infectious Diseases, University Hospital, Lausanne, Switzerland.
  • Nemeth J; Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland.
  • Kouyos RD; Cantonal Hospital St Gallen, Division of Infectious Diseases and Hospital Epidemiology, St Gallen, Switzerland.
J Infect Dis ; 225(12): 2229-2234, 2022 06 15.
Article in En | MEDLINE | ID: mdl-35172332
While an increased risk of active and latent tuberculosis infection (LTBI) in people with type-2 diabetes (DM) has been demonstrated, it is less well characterized whether LTBI is associated with an increased risk of developing DM. We investigated the link between LTBI and DM in people living with HIV in the Swiss HIV Cohort Study via time-dependent Cox proportional hazards models. We found that LTBI significantly increased the risk of developing DM (HR = 1.47), which was robust across different adjustment and censoring techniques. Our results thus suggest that LTBI may be associated with an increased risk of developing DM.
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: HIV Infections / Diabetes Mellitus, Type 2 / Latent Tuberculosis Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Infect Dis Year: 2022 Document type: Article

Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: HIV Infections / Diabetes Mellitus, Type 2 / Latent Tuberculosis Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Infect Dis Year: 2022 Document type: Article