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CDC7 kinase (DDK) inhibition disrupts DNA replication leading to mitotic catastrophe in Ewing sarcoma.
Martin, Jeffrey C; Sims, Jennie R; Gupta, Ajay; Hagoel, Tamara J; Gao, Lingqiu; Lynch, Miranda L; Woloszynska, Anna; Melendy, Thomas; Kane, Jeremy F; Kuechle, Joseph; Ohm, Joyce E.
Affiliation
  • Martin JC; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Sims JR; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Gupta A; Division of Pediatric Oncology, Roswell Park Comprehensive Cancer Center, Department of Pediatrics, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
  • Hagoel TJ; Division of Pediatric Oncology, Roswell Park Comprehensive Cancer Center, Department of Pediatrics, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
  • Gao L; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Lynch ML; Hauptman-Woodward Medical Research Institute, Buffalo, NY, USA.
  • Woloszynska A; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Melendy T; Department of Microbiology and Immunology, State University of New York at Buffalo, Buffalo, NY, USA.
  • Kane JF; Department of Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Kuechle J; Department of Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Ohm JE; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. joyce.ohm@roswellpark.org.
Cell Death Discov ; 8(1): 85, 2022 Feb 26.
Article in En | MEDLINE | ID: mdl-35220396
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 7_ODS3_muertes_prevenibles_nacidos_ninos Database: MEDLINE Language: En Journal: Cell Death Discov Year: 2022 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 7_ODS3_muertes_prevenibles_nacidos_ninos Database: MEDLINE Language: En Journal: Cell Death Discov Year: 2022 Document type: Article