Possible Synergistic Role of Cryo-Alcohol Therapy in Infectious Scleritis-Scope and Rationale for Expanding Indications and Review of the Literature.
Cornea
; 42(2): 194-203, 2023 Feb 01.
Article
in En
| MEDLINE
| ID: mdl-35249984
ABSTRACT
PURPOSE:
The purpose of this study was to highlight the use of topical ethanol as an adjunct to cryotherapy, termed cryo-alcohol therapy, in the management of fungal/acanthamoeba scleritis along with a review of the literature.METHOD:
Retrospective interventional case reports of fungal and acanthamoeba scleritis along with a review of the literature.RESULTS:
The patient with circumferential necrotic fungal scleritis resolved in 6 weeks achieving a best-corrected visual acuity (BCVA) of 20/20, and the patient with acanthamoeba scleritis is awaiting optical keratoplasty after complete resolution in 8 weeks. The literature review from January 1990 to December 2020 revealed BCVA >20/200 in 50% of the eyes with a mean time to resolution being 4.16 ± 2.13 months in fungal scleritis, with 27.02% and 75% of the eyes requiring evisceration in fungal and acanthamoeba scleritis, respectively.CONCLUSIONS:
Cryotherapy is a useful adjunct in managing refractory infectious scleritis, and its efficacy can be enhanced by combining the use of topical ethanol to aid in faster recovery and reduce visual morbidity.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Acanthamoeba
/
Acanthamoeba Keratitis
/
Scleritis
Limits:
Humans
Language:
En
Journal:
Cornea
Year:
2023
Document type:
Article