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A thermostable Cas12b from Brevibacillus leverages one-pot discrimination of SARS-CoV-2 variants of concern.
Nguyen, Long T; Macaluso, Nicolas C; Pizzano, Brianna L M; Cash, Melanie N; Spacek, Jan; Karasek, Jan; Miller, Megan R; Lednicky, John A; Dinglasan, Rhoel R; Salemi, Marco; Jain, Piyush K.
Affiliation
  • Nguyen LT; Department of Chemical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA.
  • Macaluso NC; Department of Chemical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA.
  • Pizzano BLM; Department of Agricultural and Biological Engineering, College of Agricultural and Life Sciences, University of Florida, Gainesville, FL, USA.
  • Cash MN; Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Spacek J; Sparsek S.R.O., Príkop 838/6, Zábrdovice, Brno 60200, Czech Republic.
  • Karasek J; SCIERING S.R.O., Príkop 838/6, Zábrdovice, Brno 62100, Czech Republic.
  • Miller MR; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
  • Lednicky JA; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA.
  • Dinglasan RR; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
  • Salemi M; Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Jain PK; Department of Chemical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA; UF Health Cancer Center, University of Florida, Gainesville, FL, USA. Electronic address: Jainp@ufl.edu.
EBioMedicine ; 77: 103926, 2022 Mar.
Article in En | MEDLINE | ID: mdl-35290826
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Full text: 1 Collection: 01-internacional Health context: 4_TD Database: MEDLINE Main subject: Brevibacillus / COVID-19 Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: EBioMedicine Year: 2022 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Health context: 4_TD Database: MEDLINE Main subject: Brevibacillus / COVID-19 Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: EBioMedicine Year: 2022 Document type: Article