Is sudden deafness in non-diabetic patients affected by their glycosylated hemoglobin levels?
Eur Rev Med Pharmacol Sci
; 26(5): 1668-1673, 2022 Mar.
Article
in En
| MEDLINE
| ID: mdl-35302214
ABSTRACT
OBJECTIVE:
Though the incidence of sudden sensorineural hearing loss (SSNHL) is relatively low, the disorder has a major impact on the quality of life of patients. Identifying biological markers for the disease will be useful, especially in resource-scarce areas. Our study aims to evaluate the correlation between the degree of hearing impairment and glycosylated hemoglobin (HbA1c) in patients with SSNHL. PATIENTS ANDMETHODS:
One hundred and thirty-eight patients with SSNHL and no history of diabetes were included in this study. The intravenous HbA1c content before treatment was correlated with the pure tone audiogram (PTA) average as per the criteria for SSNHL. Spearman correlation and the Receiver Operating Characteristic (ROC) curve were used to determine the HbA1c levels of the study participants. The critical value of HbA1c and its diagnostic implications for assessing the degree of hearing impairment in patients with SSNHL were noted.RESULTS:
There was a significant positive correlation between HbA1c and PTA in patients with SSNHL (p<0.05). In addition, the best HbA1c cutoff value for screening and referring an individual for a detailed audiometric evaluation of hearing impairment was 5.550%, as indicated by the ROC curve.CONCLUSIONS:
The level of HbA1c in the circulation may affect the onset, duration, and progression of SSNHL. The same parameter may be used as a diagnostic and prognostic indicator for this condition.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hearing Loss, Sudden
/
Hearing Loss, Sensorineural
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Humans
Language:
En
Journal:
Eur Rev Med Pharmacol Sci
Year:
2022
Document type:
Article