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An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Marjault, Henri-Baptiste; Karmi, Ola; Zuo, Ke; Michaeli, Dorit; Eisenberg-Domovich, Yael; Rossetti, Giulia; de Chassey, Benoit; Vonderscher, Jacky; Cabantchik, Ioav; Carloni, Paolo; Mittler, Ron; Livnah, Oded; Meldrum, Eric; Nechushtai, Rachel.
Affiliation
  • Marjault HB; The Alexander Silberman Institute of Life Science and The Wolfson Centre for Applied Structural Biology, Faculty of Science and Mathematics, The Edmond J. Safra Campus at Givat Ram, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
  • Karmi O; Department of Physics, RWTH Aachen University, 52074, Aachen, Germany.
  • Zuo K; The Alexander Silberman Institute of Life Science and The Wolfson Centre for Applied Structural Biology, Faculty of Science and Mathematics, The Edmond J. Safra Campus at Givat Ram, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
  • Michaeli D; Department of Surgery, University of Missouri School of Medicine, and Interdisciplinary Plant Group, Christopher S. Bond Life Sciences Center, University of Missouri, 1201 Rollins St, Columbia, MO, 65211, USA.
  • Eisenberg-Domovich Y; The Alexander Silberman Institute of Life Science and The Wolfson Centre for Applied Structural Biology, Faculty of Science and Mathematics, The Edmond J. Safra Campus at Givat Ram, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
  • Rossetti G; Department of Physics, RWTH Aachen University, 52074, Aachen, Germany.
  • de Chassey B; The Alexander Silberman Institute of Life Science and The Wolfson Centre for Applied Structural Biology, Faculty of Science and Mathematics, The Edmond J. Safra Campus at Givat Ram, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
  • Vonderscher J; The Alexander Silberman Institute of Life Science and The Wolfson Centre for Applied Structural Biology, Faculty of Science and Mathematics, The Edmond J. Safra Campus at Givat Ram, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
  • Cabantchik I; Department of Physics, RWTH Aachen University, 52074, Aachen, Germany.
  • Carloni P; Computational Biomedicine Section, Institute of Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
  • Mittler R; Computational Biomedicine, Institute of Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, For-schungszentrum Jülich GmbH, 52425, Jülich, Germany.
  • Livnah O; ENYO-Pharma, Bioserra 1, 60 Avenue Rockefeller Bâtiment B, 69008, Lyon, France.
  • Meldrum E; ENYO-Pharma, Bioserra 1, 60 Avenue Rockefeller Bâtiment B, 69008, Lyon, France.
  • Nechushtai R; The Alexander Silberman Institute of Life Science and The Wolfson Centre for Applied Structural Biology, Faculty of Science and Mathematics, The Edmond J. Safra Campus at Givat Ram, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
Commun Biol ; 5(1): 437, 2022 05 10.
Article in En | MEDLINE | ID: mdl-35538231
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Experimental / Iron-Sulfur Proteins Limits: Animals Language: En Journal: Commun Biol Year: 2022 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Experimental / Iron-Sulfur Proteins Limits: Animals Language: En Journal: Commun Biol Year: 2022 Document type: Article