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Defective AMPK regulation of cholesterol metabolism accelerates atherosclerosis by promoting HSPC mobilization and myelopoiesis.
Lee, Man K S; Cooney, Olivia D; Lin, Xuzhu; Nadarajah, Shaktypreya; Dragoljevic, Dragana; Huynh, Kevin; Onda, Danise-Ann; Galic, Sandra; Meikle, Peter J; Edlund, Thomas; Fullerton, Morgan D; Kemp, Bruce E; Murphy, Andrew J; Loh, Kim.
Affiliation
  • Lee MKS; Division of Immunometabolism, Baker Heart and Diabetes Institute, Melbourne, Australia; Department of Diabetes, Monash University, Melbourne, Australia; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.
  • Cooney OD; Division of Immunometabolism, Baker Heart and Diabetes Institute, Melbourne, Australia; Department of Diabetes, Monash University, Melbourne, Australia.
  • Lin X; Diabetes and Metabolic Disease, St. Vincent's Institute of Medical Research, Fitzroy, Australia.
  • Nadarajah S; Diabetes and Metabolic Disease, St. Vincent's Institute of Medical Research, Fitzroy, Australia.
  • Dragoljevic D; Division of Immunometabolism, Baker Heart and Diabetes Institute, Melbourne, Australia; Department of Diabetes, Monash University, Melbourne, Australia; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.
  • Huynh K; Metabolomics Laboratory, Baker Heart and Diabetes Institute; Melbourne, Australia.
  • Onda DA; Diabetes and Metabolic Disease, St. Vincent's Institute of Medical Research, Fitzroy, Australia.
  • Galic S; Protein Chemistry and Metabolism, St. Vincent's Institute of Medical Research, Fitzroy, Australia; Department of Medicine, University of Melbourne, Melboourne, Australia.
  • Meikle PJ; Department of Diabetes, Monash University, Melbourne, Australia; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia; Metabolomics Laboratory, Baker Heart and Diabetes Institute; Melbourne, Australia.
  • Edlund T; Umeå Centre for Molecular Medicine, Umeå University, Umeå, Sweden; Betagenon AB; Västra Strandgatan 9B, 903 26, Umeå, Sweden.
  • Fullerton MD; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, Centre for Infection, Immunity and Inflammation, Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, Canada.
  • Kemp BE; Protein Chemistry and Metabolism, St. Vincent's Institute of Medical Research, Fitzroy, Australia; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia; Department of Medicine, University of Melbourne, Melboourne, Australia.
  • Murphy AJ; Division of Immunometabolism, Baker Heart and Diabetes Institute, Melbourne, Australia; Department of Diabetes, Monash University, Melbourne, Australia; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia; Department of Medicine, University of Melbourne, Melboourne, A
  • Loh K; Diabetes and Metabolic Disease, St. Vincent's Institute of Medical Research, Fitzroy, Australia; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia; Department of Medicine, University of Melbourne, Melboourne, Australia. Electronic address: kloh@svi.ed
Mol Metab ; 61: 101514, 2022 07.
Article in En | MEDLINE | ID: mdl-35562083
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myelopoiesis / Atherosclerosis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Metab Year: 2022 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myelopoiesis / Atherosclerosis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Metab Year: 2022 Document type: Article