Structural Modeling of TRPA1 Ion Channel-Determination of the Binding Site for Antagonists.

Gawalska, Alicja; Kolaczkowski, Marcin; Bucki, Adam

Gawalska, Alicja; Kolaczkowski, Marcin; Bucki, Adam.

Affiliation

Gawalska A; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Cracow, Poland.
Kolaczkowski M; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Cracow, Poland.
Bucki A; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Cracow, Poland.

Molecules ; 27(10)2022 May 11.

Article in En | MEDLINE | ID: mdl-35630553

Subject(s)

Calcium Channels; Xanthines; Binding Sites; Calcium Channels/metabolism; Hypoxanthines; Retrospective Studies; TRPA1 Cation Channel/genetics; TRPA1 Cation Channel/metabolism

Key words

COPD; HC-030031; TRPA1; TRPA1 antagonists; asthma; molecular modeling

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xanthines / Calcium Channels Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Molecules Year: 2022 Document type: Article

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