Two new isoflavones from the roots of Sophora tonkinensis.
J Asian Nat Prod Res
; 25(2): 163-170, 2023 Feb.
Article
in En
| MEDLINE
| ID: mdl-35675145
Two new isoflavones (1 and 2), as well as eight known ones were isolated from the roots of Sophora tonkinensis Gagnep. Compound 1 represents an unprecedented polymerization pattern constructed by isoflavone and cytisine. Their structures were elucidated by comprehensive spectroscopic data analysis, combined with ECD calculations. Compound 1 displayed significant anti-tobacco mosaic virus (TMV) activity compared with the positive control ningnanmycin. Moreover, compound 6 exhibited potent α-glucosidase inhibitory activity with IC50 value of 47.4 mg/L.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sophora
/
Alkaloids
/
Isoflavones
Language:
En
Journal:
J Asian Nat Prod Res
Year:
2023
Document type:
Article