The selective 5-HT 1A receptor agonist, NLX-112, overcomes tetrabenazine-induced catalepsy and depression-like behavior in the rat.

Jastrzebska-Wiesek, Magdalena; Wesolowska, Anna; Kolaczkowski, Marcin; Varney, Mark A; Newman-Tancredi, Adrian; Depoortere, RonanY

Jastrzebska-Wiesek, Magdalena; Wesolowska, Anna; Kolaczkowski, Marcin; Varney, Mark A; Newman-Tancredi, Adrian; Depoortere, RonanY.

Affiliation

Jastrzebska-Wiesek M; Department of Clinical Pharmacy, Jagiellonian University Medical College, Faculty of Pharmacy, Kraków, Poland.
Wesolowska A; Department of Clinical Pharmacy, Jagiellonian University Medical College, Faculty of Pharmacy, Kraków, Poland.
Kolaczkowski M; Department of Clinical Pharmacy, Jagiellonian University Medical College, Faculty of Pharmacy, Kraków, Poland.
Varney MA; Neurolixis SAS, Castres, France.
Newman-Tancredi A; Neurolixis SAS, Castres, France.
Depoortere R; Neurolixis SAS, Castres, France.

Behav Pharmacol ; 33(5): 333-341, 2022 08 01.

Article in En | MEDLINE | ID: mdl-35695543

Subject(s)

Huntington Disease; Parkinsonian Disorders; 8-Hydroxy-2-(di-n-propylamino)tetralin/pharmacology; Animals; Antidepressive Agents/pharmacology; Buspirone/pharmacology; Catalepsy/chemically induced; Catalepsy/drug therapy; Depression/chemically induced; Depression/drug therapy; Huntington Disease/chemically induced; Huntington Disease/drug therapy; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists/pharmacology; Serotonin Receptor Agonists/pharmacology; Tetrabenazine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease / Parkinsonian Disorders Limits: Animals Language: En Journal: Behav Pharmacol Year: 2022 Document type: Article

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