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Alpha-kinase 1 (ALPK1) agonist DF-006 demonstrates potent efficacy in mouse and primary human hepatocyte (PHH) models of hepatitis B.
Xu, Cong; Fan, Jieqing; Liu, Danyang; Tuerdi, Aimaier; Chen, Juanjuan; Wei, Yuning; Pan, Yanfang; Dang, Huaixin; Wei, Xiong; Yousif, Ashraf Siddig; Yogaratnam, Jeysen; Zhou, Qiong; Lichenstein, Henri; Xu, Tian.
Affiliation
  • Xu C; Shanghai Yao Yuan Biotechnology Ltd (Drug Farm) , Shanghai , China.
  • Fan J; Zhejiang Yao Yuan Biotechnology Ltd , Jiashan , Zhejiang , China.
  • Liu D; Shanghai Yao Yuan Biotechnology Ltd (Drug Farm) , Shanghai , China.
  • Tuerdi A; Zhejiang Yao Yuan Biotechnology Ltd , Jiashan , Zhejiang , China.
  • Chen J; Shanghai Yao Yuan Biotechnology Ltd (Drug Farm) , Shanghai , China.
  • Wei Y; Zhejiang Yao Yuan Biotechnology Ltd , Jiashan , Zhejiang , China.
  • Pan Y; Shanghai Yao Yuan Biotechnology Ltd (Drug Farm) , Shanghai , China.
  • Dang H; Shanghai Yao Yuan Biotechnology Ltd (Drug Farm) , Shanghai , China.
  • Wei X; Shanghai Yao Yuan Biotechnology Ltd (Drug Farm) , Shanghai , China.
  • Yousif AS; Shanghai Yao Yuan Biotechnology Ltd (Drug Farm) , Shanghai , China.
  • Yogaratnam J; Zhejiang Yao Yuan Biotechnology Ltd , Jiashan , Zhejiang , China.
  • Zhou Q; Shanghai Yao Yuan Biotechnology Ltd (Drug Farm) , Shanghai , China.
  • Lichenstein H; Drug Farm USA , Lowell , Massachusetts , USA.
  • Xu T; Drug Farm USA , Lowell , Massachusetts , USA.
Hepatology ; 77(1): 275-289, 2023 01 01.
Article in En | MEDLINE | ID: mdl-35699669
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Hepatitis B, Chronic / Hepatitis B Limits: Animals / Humans Language: En Journal: Hepatology Year: 2023 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Hepatitis B, Chronic / Hepatitis B Limits: Animals / Humans Language: En Journal: Hepatology Year: 2023 Document type: Article