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A Natural Dihydropyridazinone Scaffold Generated from a Unique Substrate for a Hydrazine-Forming Enzyme.
Matsuda, Kenichi; Arima, Kuga; Akiyama, Satoko; Yamada, Yuito; Abe, Yo; Suenaga, Hikaru; Hashimoto, Junko; Shin-Ya, Kazuo; Nishiyama, Makoto; Wakimoto, Toshiyuki.
Affiliation
  • Matsuda K; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812, Japan.
  • Arima K; Global Station for Biosurfaces and Drug Discovery, Global Institution for Collaborative Research and Education, Hokkaido University, Kita 12, Nishi 6, Sapporo 060-0812, Japan.
  • Akiyama S; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812, Japan.
  • Yamada Y; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812, Japan.
  • Abe Y; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812, Japan.
  • Suenaga H; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812, Japan.
  • Hashimoto J; National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan.
  • Shin-Ya K; Japan Biological Informatics Consortium (JBIC), Tokyo 135-0064, Japan.
  • Nishiyama M; National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan.
  • Wakimoto T; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
J Am Chem Soc ; 144(28): 12954-12960, 2022 07 20.
Article in En | MEDLINE | ID: mdl-35771530
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / Multigene Family Language: En Journal: J Am Chem Soc Year: 2022 Document type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / Multigene Family Language: En Journal: J Am Chem Soc Year: 2022 Document type: Article