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Improving the solubility and antileukemia activity of Wnt/ß-catenin signaling inhibitors by disrupting molecular planarity.
Ai, Yong; Sakamuru, Srilatha; Imler, Greg; Xia, Menghang; Xue, Fengtian.
Affiliation
  • Ai Y; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, United States.
  • Sakamuru S; 9800 Medical Center Drive, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, United States.
  • Imler G; Naval Research Laboratory, Code 6930, 4555 Overlook Avenue, Washington, D.C. 20375, United States.
  • Xia M; 9800 Medical Center Drive, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, United States.
  • Xue F; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, United States. Electronic address: fxue@rx.umaryland.edu.
Bioorg Med Chem ; 69: 116890, 2022 09 01.
Article in En | MEDLINE | ID: mdl-35777269
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Wnt Signaling Pathway Limits: Humans Language: En Journal: Bioorg Med Chem Year: 2022 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Wnt Signaling Pathway Limits: Humans Language: En Journal: Bioorg Med Chem Year: 2022 Document type: Article