Choroidal and retinal thickness in patients with vitamin C deficiency using swept-source optical coherence tomography.
BMC Ophthalmol
; 22(1): 311, 2022 Jul 18.
Article
in En
| MEDLINE
| ID: mdl-35850684
ABSTRACT
BACKGROUND:
To investigate the effects of vitamin C on central retinal thickness and choroidal thickness.METHODS:
A total of 69 patients diagnosed with vitamin C deficiency and 11 age- and gender-matched 69 healthy individuals with normal serum vitamin C were included in this study. Demographic characteristics of the individuals were collected. All patients underwent a comprehensive ophthalmic examination. Subfoveal choroidal thickness and retinal thickness were measured using a swept-source optical coherence tomography (SS-OCT).RESULTS:
The average retinal thickness was 269.07 ± 13.51 µm in the vitamin C deficiency group and 276.92 ± 13.51 µm in the control group. The average choroidal thickness was 195.62 ± 66.40 µm in the in the vitamin C deficiency group and 238.86 ± 55.08 µm in the control group. There was a significant decrease in both average choroidal thickness and retinal thickness in vitamin C deficiency group compared with normal individuals (p < 0.001, and = 0.001 respectively).CONCLUSION:
The central retinal and choroidal thickness were thinner in vitamin C deficiency group compared with normal individuals. These findings suggested that vitamin C deficiency might play an important role in retinal and choroidal diseases.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ascorbic Acid Deficiency
/
Tomography, Optical Coherence
Limits:
Humans
Language:
En
Journal:
BMC Ophthalmol
Year:
2022
Document type:
Article