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Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders.
Bryois, Julien; Calini, Daniela; Macnair, Will; Foo, Lynette; Urich, Eduard; Ortmann, Ward; Iglesias, Victor Alejandro; Selvaraj, Suresh; Nutma, Erik; Marzin, Manuel; Amor, Sandra; Williams, Anna; Castelo-Branco, Gonçalo; Menon, Vilas; De Jager, Philip; Malhotra, Dheeraj.
Affiliation
  • Bryois J; Neuroscience and Rare Diseases, F. Hoffmann-La Roche Ltd., Basel, Switzerland. julien.bryois@roche.com.
  • Calini D; Neuroscience and Rare Diseases, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Macnair W; Neuroscience and Rare Diseases, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Foo L; Neuroscience and Rare Diseases, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Urich E; Neuroscience and Rare Diseases, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Ortmann W; Genentech, South San Francisco, CA, USA.
  • Iglesias VA; Genentech, South San Francisco, CA, USA.
  • Selvaraj S; Genentech, South San Francisco, CA, USA.
  • Nutma E; Pathology Department, VUmc, Amsterdam UMC, Amsterdam, Netherlands.
  • Marzin M; Pathology Department, VUmc, Amsterdam UMC, Amsterdam, Netherlands.
  • Amor S; Pathology Department, VUmc, Amsterdam UMC, Amsterdam, Netherlands.
  • Williams A; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Castelo-Branco G; Centre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
  • Menon V; Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • De Jager P; Ming Wai Lau Centre for Reparative Medicine, Stockholm Node, Karolinska Institutet, Stockholm, Sweden.
  • Malhotra D; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
Nat Neurosci ; 25(8): 1104-1112, 2022 08.
Article in En | MEDLINE | ID: mdl-35915177
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome-Wide Association Study / Nervous System Diseases Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Neurosci Year: 2022 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome-Wide Association Study / Nervous System Diseases Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Neurosci Year: 2022 Document type: Article