Real-world health outcomes in US adult patients with mild to moderate plaque psoriasis taking topical therapy.
J Dermatolog Treat
; 33(6): 2844-2852, 2022 Sep.
Article
in En
| MEDLINE
| ID: mdl-35920355
ABSTRACT
BACKGROUND:
Limited health outcomes information exists for patients with mild to moderate plaque psoriasis (hereafter, referred to as psoriasis) prescribed topical treatment(s).AIM:
We evaluated clinical characteristics of patients with systemic-naïve mild to moderate psoriasis after topical use in the United States.METHODS:
Data were drawn from 2017 to 2018 Adelphi Psoriasis Disease Specific Programme™, a point-in-time survey of physicians and adult psoriasis patients, capturing data on topical treatment at time of consultation prescribed to systemic-naïve patients with mild to moderate psoriasis (i.e. body surface area [BSA] ≤ 10%) at current treatment initiation. Patient clinical characteristics before/after topical use were evaluated descriptively.RESULTS:
Among 304 patients (median age 43.0 years; 53.6% female), mean time since diagnosis was 60.9 months. After a mean 6.9 months on their current topical, 14.5% of patients achieved ≥75% BSA reduction, 38.9% ≥50% BSA reduction, and 50.2% no BSA reduction. Residual psoriasis symptoms included scaling (76.5%), inflamed skin (65.9%), and itching (60.4%). Most patients (71.2%) had residual psoriasis in special body areas nails (92.3%), palmoplantar (78.9%), scalp (75.9%), and face (65.8%).CONCLUSION:
We found unmet need in topical treatment effectiveness in mild to moderate psoriasis patients, in terms of BSA reduction, symptoms, and special body areas affected.Key words
Full text:
1
Collection:
01-internacional
Health context:
2_ODS3
Database:
MEDLINE
Main subject:
Psoriasis
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
America do norte
Language:
En
Journal:
J Dermatolog Treat
Year:
2022
Document type:
Article