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Designing and executing prime editing experiments in mammalian cells.
Doman, Jordan L; Sousa, Alexander A; Randolph, Peyton B; Chen, Peter J; Liu, David R.
Affiliation
  • Doman JL; Merkin Institute of Transformative Technologies in Healthcare, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Sousa AA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Randolph PB; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
  • Chen PJ; Merkin Institute of Transformative Technologies in Healthcare, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Liu DR; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
Nat Protoc ; 17(11): 2431-2468, 2022 11.
Article in En | MEDLINE | ID: mdl-35941224

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CRISPR-Cas Systems / Gene Editing Type of study: Guideline Limits: Animals / Humans Language: En Journal: Nat Protoc Year: 2022 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CRISPR-Cas Systems / Gene Editing Type of study: Guideline Limits: Animals / Humans Language: En Journal: Nat Protoc Year: 2022 Document type: Article