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Diagnosis of hepatic steatosis based on ultrasound attenuation imaging is not influenced by liver fibrosis.
Yuri, Minako; Nishimura, Takashi; Tada, Toshifumi; Yoshida, Masahiro; Fujiwara, Aoi; Kawata, Shoki; Yoshihara, Kohei; Yoshioka, Ryota; Ota, Shogo; Nakano, Ryota; Yuri, Yukihisa; Takashima, Tomoyuki; Aizawa, Nobuhiro; Ikeda, Naoto; Shiomi, Hideyuki; Ide, Yoshi-Hiro; Enomoto, Hirayuki; Yasuhiro, Fujimoto; Yano, Hirohisa; Iijima, Hiroko.
Affiliation
  • Yuri M; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Nishimura T; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Tada T; Ultrasound Imaging Center, Hyogo Medical University, Nishinomiya, Japan.
  • Yoshida M; Department of Internal Medicine, Japanese Red Cross Society Himeji Hospital, Himeji, Japan.
  • Fujiwara A; Ultrasound Imaging Center, Hyogo Medical University, Nishinomiya, Japan.
  • Kawata S; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Yoshihara K; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Yoshioka R; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Ota S; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Nakano R; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Yuri Y; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Takashima T; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Aizawa N; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Ikeda N; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Shiomi H; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Ide YH; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Enomoto H; Department of Pathology, Hyogo Medical University, Nishinomiya, Japan.
  • Yasuhiro F; Department of Gastroenterology and Hepatology, Hyogo Medical University, Nishinomiya, Japan.
  • Yano H; Department of Surgery, Hyogo Medical University, Nishinomiya, Japan.
  • Iijima H; Department of Pathology, Kurume University School of Medicine, Kurume, Japan.
Hepatol Res ; 52(12): 1009-1019, 2022 Dec.
Article in En | MEDLINE | ID: mdl-36018852
ABSTRACT

AIM:

Recently, a new technique using attenuation imaging (ATI) was developed to diagnose hepatic steatosis. The aim of this study was to investigate whether ATI for the evaluation of hepatic steatosis is influenced by liver fibrosis.

METHODS:

A total of 328 patients with chronic liver disease were enrolled to study the associations between histological hepatic steatosis or liver fibrosis and ATI findings. The interaction between liver fibrosis and ATI was also analyzed.

RESULTS:

Median ATI values according to steatosis grade and fibrosis stage increased in line with the progression of liver steatosis (p < 0.001) and fibrosis (p < 0.05). However, in each steatosis grade, ATI values according to fibrosis stage were not significantly increased. In multiple regression analyses for assessment of the effect of their interaction, the p values for fibrosis stage, steatosis grade, and fibrosis stage × steatosis grade were 0.096, <0.001, and 0.077, respectively. Variance inflation factor values for fibrosis stage, steatosis grade, and fibrosis stage × steatosis grade were 1.079, 1.094, and 1.074, respectively.

CONCLUSION:

Attenuation imaging values are not influenced by liver fibrosis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: Hepatol Res Year: 2022 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: Hepatol Res Year: 2022 Document type: Article