Determination of mycotoxins by HPLC, LC-MS/MS and health risk assessment of the mycotoxins in bee products of Turkey.

Keskin, Eda; Eyupoglu, Ozan Emre

Keskin, Eda; Eyupoglu, Ozan Emre.

Affiliation

Keskin E; Department of Nutrition and Dietetics, Institute of Health Sciences, Istanbul Medipol University, Kavacik, 34810 Istanbul, Turkey.
Eyupoglu OE; Department of Biochemistry, School of Pharmacy, Istanbul Medipol University, Kavacik, 34810 Istanbul, Turkey. Electronic address: oeeyupoglu@medipol.edu.tr.

Food Chem ; 400: 134086, 2023 Jan 30.

Article in En | MEDLINE | ID: mdl-36075166

ABSTRACT

ABSTRACT

The aim of this study is to determine the levels of deoxynivalenol (DON), HT-2 toxin (HT2), T-2 toxin (T2), and ochratoxin A (OTA) in bee products (bee pollen, propolis, honey and royal jelly) available in Turkey. In addition, exposure and health risk assessments were performed to identify the potential health risk of these mycotoxins. The mycotoxins were analyzed by high-performance liquid chromatography (HPLC) with a UV detector and positive samples were confirmed with liquid chromatography-tandem mass spectrometry (LC-MS/MS). The most common mycotoxins in all bee products were DON and T-2 toxin, with mean concentrations of 1.601 and 0.704 µg/per kg dry sample, respectively, followed by OTA and HT-2 toxin. It was determined that the mycotoxins taken as a result of consuming bee products in specified amounts do not pose a risk to health.

Subject(s)

Mycotoxins; Propolis; T-2 Toxin; Chromatography, High Pressure Liquid/methods; Chromatography, Liquid; Food Contamination/analysis; Mycotoxins/analysis; Risk Assessment; T-2 Toxin/analogs & derivatives; T-2 Toxin/analysis; Tandem Mass Spectrometry/methods; Turkey

Key words

Acetic acid (PubChem CID: 176); Acetonitrile (PubChem CID: 6342); Aluminum oxide (PubChem CID: 9989226); Bee products; Deoxynivalenol; Deoxynivalenol (PubChem CID: 40024); Formic acid (PubChem CID: 284); HPLC-UV-MS; HT-2 toxin (PubChem CID: 10093830); Margin of exposure; Methanol (PubChem CID: 887); Ochratoxin A; Ochratoxin A (PubChem CID: 442530); T-2 toxin; T-2 toxin (PubChem CID: 5284461)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / T-2 Toxin / Mycotoxins Country/Region as subject: Asia Language: En Journal: Food Chem Year: 2023 Document type: Article

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