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High Bulk-Density Amorphous Dispersions to Enable Direct Compression of Reduced Tablet Size Amorphous Dosage Units.
Frank, Derek S; Nie, Haichen; Chandra, Anagha; Coelho, Alexander; Dalton, Chad; Dvorak, Hannah; Elkhabaz, Ahmed; Fahy, Mairead; Ormes, James; Parker, Andrew; Punia, Ashish; Rowe, Jasmine; Schenck, Luke; Smith, Daniel; Strotman, Neil A; Wang, Michael; Wareham, Laura.
Affiliation
  • Frank DS; Process Research & Development, Merck & Co., Inc., Rahway, NJ, USA. Electronic address: derek.frank@merck.com.
  • Nie H; Formulation Sciences, Merck & Co., Inc., Rahway, NJ, USA. Electronic address: haichen.nie@merck.com.
  • Chandra A; Process Research & Development, Merck & Co., Inc., Rahway, NJ, USA.
  • Coelho A; Process Research & Development, Merck & Co., Inc., Rahway, NJ, USA.
  • Dalton C; Formulation Sciences, Merck & Co., Inc., Rahway, NJ, USA.
  • Dvorak H; Pharmaceutical Commercialization Technologies, Merck & Co., Inc., Rahway, NJ, USA.
  • Elkhabaz A; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ, USA.
  • Fahy M; Pharmaceutical Commercialization Technologies, Merck & Co., Inc., Rahway, NJ, USA.
  • Ormes J; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ, USA.
  • Parker A; Formulation Sciences, Merck & Co., Inc., Rahway, NJ, USA.
  • Punia A; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ, USA.
  • Rowe J; Formulation Sciences, Merck & Co., Inc., Rahway, NJ, USA.
  • Schenck L; Process Research & Development, Merck & Co., Inc., Rahway, NJ, USA.
  • Smith D; Analytical Research & Development, Merck & Co., Inc., Rahway, NJ, USA.
  • Strotman NA; Process Research & Development, Merck & Co., Inc., Rahway, NJ, USA.
  • Wang M; Biopharmaceutics, Merck & Co., Inc., Rahway, NJ, USA.
  • Wareham L; Pharmaceutical Commercialization Technologies, Merck & Co., Inc., Rahway, NJ, USA.
J Pharm Sci ; 112(8): 2037-2045, 2023 Aug.
Article in En | MEDLINE | ID: mdl-36115592

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Water Language: En Journal: J Pharm Sci Year: 2023 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Water Language: En Journal: J Pharm Sci Year: 2023 Document type: Article