Microbial lignin valorization through depolymerization to aromatics conversion.
Trends Biotechnol
; 40(12): 1469-1487, 2022 12.
Article
in En
| MEDLINE
| ID: mdl-36307230
ABSTRACT
Lignin is the most abundant source of renewable aromatic biopolymers and its valorization presents significant value for biorefinery sustainability, which promotes the utilization of renewable resources. However, it is challenging to fully convert the structurally complex, heterogeneous, and recalcitrant lignin into high-value products. The in-depth research on the lignin degradation mechanism, microbial metabolic pathways, and rational design of new systems using synthetic biology have significantly accelerated the development of lignin valorization. This review summarizes the key enzymes involved in lignin depolymerization, the mechanisms of microbial lignin conversion, and the lignin valorization application with integrated systems and synthetic biology. Current challenges and future strategies to further study lignin biodegradation and the trends of lignin valorization are also discussed.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Metabolic Networks and Pathways
/
Lignin
Language:
En
Journal:
Trends Biotechnol
Year:
2022
Document type:
Article