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Upper airway and brain protection by plasma cells: A local affair.
Cornelis, Rebecca; Shulman, Ziv.
Affiliation
  • Cornelis R; Department of Systems Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Shulman Z; Department of Systems Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: ziv.shulman@weizmann.ac.il.
Immunity ; 55(11): 1972-1974, 2022 11 08.
Article in En | MEDLINE | ID: mdl-36351370
ABSTRACT
Protecting the upper airways and brain from viral invasion through the olfactory mucosa is critical. Wellford et al. describe a barrier that restricts the passage of circulating antibodies and prevents them from reaching the olfactory mucosa. Instead, plasma cells are recruited into this site and prevent viral infection of the airways and the brain through local antibody production.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasma Cells / Respiratory System Language: En Journal: Immunity Year: 2022 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasma Cells / Respiratory System Language: En Journal: Immunity Year: 2022 Document type: Article