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The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC.
Lee, Ji-Sun; Lero, Michael W; Mercado-Matos, Jose; Zhu, Sha; Jo, Minjeong; Tocheny, Claire E; Morgan, Jennifer S; Shaw, Leslie M.
Affiliation
  • Lee JS; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA.
  • Lero MW; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA.
  • Mercado-Matos J; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA.
  • Zhu S; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA.
  • Jo M; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA.
  • Tocheny CE; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA.
  • Morgan JS; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA.
  • Shaw LM; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA. Electronic address: leslie.shaw@umassmed.edu.
Cell Rep ; 41(10): 111759, 2022 12 06.
Article in En | MEDLINE | ID: mdl-36476848
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Somatomedins / Neoplasms Language: En Journal: Cell Rep Year: 2022 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Somatomedins / Neoplasms Language: En Journal: Cell Rep Year: 2022 Document type: Article