Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management.
J Vis Exp
; (189)2022 11 30.
Article
in En
| MEDLINE
| ID: mdl-36533819
ABSTRACT
Biobanks are key research infrastructures aimed at the collection, storage, processing, and sharing of high-quality human biological samples and associated data for research, diagnosis, and personalized medicine. The Biobank for Translational and Digital Medicine Unit at the European Institute of Oncology (IEO) is a landmark in this field. Biobanks collaborate with clinical divisions, internal and external research groups, and industry, supporting patients' treatment and scientific progress, including innovative diagnostics, biomarker discovery, and clinical trial design. Given the central role of biobanks in modern research, biobanking standard operating procedures (SOPs) should be extremely precise. SOPs and controls by certified specialists ensure the highest quality of samples for the implementation of science-based, diagnostic, prognostic, and therapeutic personalized strategies. However, despite numerous efforts to standardize and harmonize biobanks, these protocols, which follow a strict set of rules, quality controls, and guidelines based on ethical and legal principles, are not easily accessible. This paper presents the biobank standard operating procedures of a large cancer center.
Full text:
1
Collection:
01-internacional
Health context:
1_ASSA2030
Database:
MEDLINE
Main subject:
Biological Specimen Banks
/
Biomedical Research
Type of study:
Clinical_trials
/
Guideline
Aspects:
Ethics
Limits:
Humans
Language:
En
Journal:
J Vis Exp
Year:
2022
Document type:
Article