Your browser doesn't support javascript.
loading
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Butler, Christopher C; Hobbs, F D Richard; Gbinigie, Oghenekome A; Rahman, Najib M; Hayward, Gail; Richards, Duncan B; Dorward, Jienchi; Lowe, David M; Standing, Joseph F; Breuer, Judith; Khoo, Saye; Petrou, Stavros; Hood, Kerenza; Nguyen-Van-Tam, Jonathan S; Patel, Mahendra G; Saville, Benjamin R; Marion, Joe; Ogburn, Emma; Allen, Julie; Rutter, Heather; Francis, Nick; Thomas, Nicholas P B; Evans, Philip; Dobson, Melissa; Madden, Tracie-Ann; Holmes, Jane; Harris, Victoria; Png, May Ee; Lown, Mark; van Hecke, Oliver; Detry, Michelle A; Saunders, Christina T; Fitzgerald, Mark; Berry, Nicholas S; Mwandigha, Lazaro; Galal, Ushma; Mort, Sam; Jani, Bhautesh D; Hart, Nigel D; Ahmed, Haroon; Butler, Daniel; McKenna, Micheal; Chalk, Jem; Lavallee, Layla; Hadley, Elizabeth; Cureton, Lucy; Benysek, Magdalena; Andersson, Monique; Coates, Maria; Barrett, Sarah.
Affiliation
  • Butler CC; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK. Electronic address: christopher.butler@phc.ox.ac.uk.
  • Hobbs FDR; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Gbinigie OA; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Rahman NM; Oxford Respiratory Trials Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK; Oxford National Institute for Health and Care Research Biomedical Research Centre, Oxford, UK.
  • Hayward G; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Richards DB; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Dorward J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
  • Lowe DM; Institute of Immunity and Transplantation, University College London, London, UK.
  • Standing JF; Infection, Inflammation and Immunology, UCL Great Ormond Street Institute of Child Health, London, UK; Department of Pharmacy, Great Ormond Street Hospital for Children, London, UK.
  • Breuer J; Infection, Inflammation and Immunology, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Khoo S; Department of Pharmacology, University of Liverpool, Liverpool, UK.
  • Petrou S; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Hood K; Centre for Trials Research, Cardiff University, Cardiff, UK.
  • Nguyen-Van-Tam JS; Lifespan and Population Health Unit, University of Nottingham School of Medicine, Nottingham, UK.
  • Patel MG; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Saville BR; Berry Consultants, Austin, TX, USA; Department of Biostatistics, Vanderbilt School of Medicine, Nashville, TN, USA.
  • Marion J; Berry Consultants, Austin, TX, USA.
  • Ogburn E; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Allen J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Rutter H; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Francis N; Primary Care Research Centre, University of Southampton, Southampton, UK.
  • Thomas NPB; Windrush Medical Practice, Witney, UK; National Institute for Health and Care Research Clinical Research Network: Thames Valley and South Midlands, Oxford, UK; Royal College of General Practitioners, London, UK.
  • Evans P; Faculty of Health and Life Sciences, University of Exeter, Exeter, UK; National Institute for Health and Care Research Clinical Research Network, Leeds, UK.
  • Dobson M; Oxford Respiratory Trials Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Madden TA; Centre for Trials Research, Cardiff University, Cardiff, UK.
  • Holmes J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Harris V; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Png ME; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Lown M; Primary Care Research Centre, University of Southampton, Southampton, UK.
  • van Hecke O; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Detry MA; Berry Consultants, Austin, TX, USA.
  • Saunders CT; Berry Consultants, Austin, TX, USA.
  • Fitzgerald M; Berry Consultants, Austin, TX, USA.
  • Berry NS; Berry Consultants, Austin, TX, USA.
  • Mwandigha L; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Galal U; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Mort S; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Jani BD; General Practice and Primary Care, School of Health and Wellbeing, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK.
  • Hart ND; School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Ahmed H; Division of Population Medicine, Cardiff University, Cardiff, UK.
  • Butler D; School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • McKenna M; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Chalk J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Lavallee L; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Hadley E; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Cureton L; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Benysek M; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Andersson M; Department of Microbiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Coates M; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Barrett S; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Lancet ; 401(10373): 281-293, 2023 01 28.
Article in En | MEDLINE | ID: mdl-36566761
Subject(s)
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 / 2_ODS3 / 4_TD / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: COVID-19 Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Humans / Middle aged Language: En Journal: Lancet Year: 2023 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 / 2_ODS3 / 4_TD / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: COVID-19 Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Humans / Middle aged Language: En Journal: Lancet Year: 2023 Document type: Article