Mild Hypothermia Alleviates CLP-induced Multiple Organ Dysfunction by Mitigating Pyroptosis Through the TLR4/NF-&#954;B/NLRP3 Signaling Pathway.

Jiang, Liangyan; Li, Xiaorong; Hu, Juntao; Tang, Zhanhong

Mild Hypothermia Alleviates CLP-induced Multiple Organ Dysfunction by Mitigating Pyroptosis Through the TLR4/NF-κB/NLRP3 Signaling Pathway.

Jiang, Liangyan; Li, Xiaorong; Hu, Juntao; Tang, Zhanhong.

Affiliation

Jiang L; Intensive Care Unit, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Li X; Intensive Care Unit, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Hu J; Intensive Care Unit, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Tang Z; Intensive Care Unit, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. Electronic address: tangzhanhong139@sina.com.

Arch Med Res ; 54(1): 7-16, 2023 01.

Article in En | MEDLINE | ID: mdl-36588003

Subject(s)

Hypothermia; Sepsis; Rats; Animals; NF-kappa B/metabolism; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/metabolism; NLR Family, Pyrin Domain-Containing 3 Protein; Multiple Organ Failure/etiology; Multiple Organ Failure/prevention & control; Pyroptosis; Hypothermia/complications; Signal Transduction; Punctures; Sepsis/complications

Key words

Mild hypothermia; Multiple organ failure; Pyroptosis; Sepsis; Toll-like receptor

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sepsis / Hypothermia Type of study: Etiology_studies Limits: Animals Language: En Journal: Arch Med Res Year: 2023 Document type: Article

Fulltext

XML

PubMed Links

Search on Google