Impact of antiallergy agents on CPAP therapy and sleep quality with spring pollinosis in Japanese.
Sleep Breath
; 27(5): 1795-1803, 2023 10.
Article
in En
| MEDLINE
| ID: mdl-36763255
ABSTRACT
PURPOSE:
Allergic rhinitis (AR) is associated with obstructive sleep apnea (OSA) and nasal obstruction causes decreased adherence to continuous positive airway pressure (CPAP). The purpose is to evaluate the effects of antiallergic agents on CPAP adherence and sleep quality.METHODS:
A longitudinal study was made of patients who use CPAP for OSA and treated with antiallergy agents for spring pollinosis. We compared the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), nasal symptoms scores (NSS), and data from CPAP before and after treatment. Then, we classified the subjects into two groups based on the baseline PSQI score one group without a decreased sleep quality (PSQI < 6) and the other group with decreased sleep quality (PSQI ≥ 6).RESULTS:
Of 28 subjects enrolled, 13 had good sleep quality and 15 had poor sleep quality. PSQI showed significant improvements after medication (p = 0.046). ESS showed no significant differences after AR medication (p = 0.565). Significant improvement was observed after the prescription of antiallergy agents in all items of NSS (sneezing, p < 0.05; rhinorrhea, p < 0.01; nasal obstruction, p < 0.01; QOL, p < 0.01). The percentage of days with CPAP use more than 4 h increased significantly after the administration of rhinitis medication (p = 0.022). In the intragroup comparisons of PSQI ≥ 6 group, PSQI decreased significantly (p < 0.05). For the NSS in intragroup comparisons of PSQI ≥ 6 group, all parameters showed significant improvement (sneezing, p = 0.016; rhinorrhea, p = 0.005; nasal obstruction, p < 0.005; QOL, p < 0.005).CONCLUSION:
The use of antiallergy agents can improve CPAP adherence and sleep quality in patients with OSA on CPAP.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Nasal Obstruction
/
Rhinitis, Allergic, Seasonal
/
Anti-Allergic Agents
/
Sleep Apnea, Obstructive
Type of study:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Humans
Language:
En
Journal:
Sleep Breath
Year:
2023
Document type:
Article