Nuclear PTEN's Functions in Suppressing Tumorigenesis: Implications for Rare Cancers.

Langdon, Casey G

Langdon, Casey G.

Affiliation

Langdon CG; Department of Pediatrics, Darby Children's Research Institute, Medical University of South Carolina, Charleston, SC 29425, USA.

Biomolecules ; 13(2)2023 01 30.

Article in En | MEDLINE | ID: mdl-36830628

Subject(s)

Cell Nucleus; Phosphatidylinositol 3-Kinases; Adult; Humans; Child; Phosphatidylinositol 3-Kinases/metabolism; Cell Nucleus/metabolism; Cell Transformation, Neoplastic/metabolism; Cytoplasm/metabolism; PTEN Phosphohydrolase/metabolism

Key words

DNA damage; PTEN; PTEN hamartoma tumor syndrome; genetically engineered mouse models; nuclear PTEN; nuclear import; oncogenic transcriptional regulation; post-translational modifications; subcellular localization

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Nucleus / Phosphatidylinositol 3-Kinases Limits: Adult / Child / Humans Language: En Journal: Biomolecules Year: 2023 Document type: Article

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